This week we hosted two close friends and researchers to talk about their work in autism. They focus on cellular pathways that are commonly altered in patients with syndromic autism to both understand the physical changes that characterize neurons in the brain of a patient with autism and also create animal models that best represent human autism so we can understand the disorder and work towards therapies. You can see in the chart below that most of the genetic contributions that lead to autism are unknown. We hope you enjoy our analysis of and opinions on what we know and don’t know and how we study this complex disorder.